Medicine shortages United States — current list

226 substances are currently on the shortage list in United States. Source: FDA — Drug Shortages (openFDA).

Source: FDA — Drug Shortages (openFDA) · As of: 10/16/2026

• Amino Acid Injectionunavailable · for 3 days
• Amphetamine Aspartate Monohydrate, Amphetamine Sulfate, Dextroamphetamine Saccharate, Dextroamphetamine Sulfate Tabletunavailable · for 3 days
• Atropine Sulfate Injectionunavailable · for 4 days
• Azacitidine Injectionunavailable · for 3 days
• Bacitracin Ophthalmic Ointmentunavailable · for 3 days
• Bupivacaine Hydrochloride Injectionunavailable · for 4 days
• Bupivacaine Hydrochloride, Epinephrine Bitartrate Injectionunavailable · for 3 days
• Carboplatin Injectionunavailable · for 4 days
• Cefotaxime Sodium Powder, for Solutionunavailable · for 3 days
• Clindamycin Phosphate Injectionunavailable · for 4 days
• Clonazepam Tabletunavailable · for 3 days
• Conivaptan Hydrochloride Injectionunavailable · for 3 days
• Cromolyn Sodium Concentrateunavailable · for 3 days
• Desmopressin Acetate Sprayunavailable · for 3 days
• Dexamethasone Sodium Phosphate Injectionunavailable · for 3 days
• Dexmedetomidine Hydrochloride Injectionunavailable · for 4 days
• Dextrose Monohydrate 5% Injectionunavailable · for 4 days
• Dobutamine Hydrochloride Injectionunavailable · for 3 days
• Dopamine Hydrochloride Injectionunavailable · for 3 days
• Echothiophate Iodide Ophthalmic Solutionunavailable · for 3 days
• Epinephrine Bitartrate, Lidocaine Hydrochloride Injectionunavailable · for 3 days
• Etomidate Injectionunavailable · for 3 days
• Fentanyl Citrate Injectionunavailable · for 3 days
• Flurazepam Hydrochloride Capsuleunavailable · for 3 days
• Furosemide Injectionunavailable · for 4 days
• Furosemide Oral Solutionunavailable · for 3 days
• Heparin Sodium Injectionunavailable · for 3 days
• Hydromorphone Hydrochloride Injectionunavailable · for 3 days
• Hydroxocobalamin Injectionunavailable · for 3 days
• Ifosfamide Injectionunavailable · for 3 days
• Isocarboxazid Tabletunavailable · for 3 days
• Ketorolac Tromethamine Injectionunavailable · for 3 days
• Lidocaine Hydrochloride Injectionunavailable · for 4 days
• Liraglutide Injectionunavailable · for 4 days
• Lisdexamfetamine Dimesylate Capsuleunavailable · for 3 days
• Lisdexamfetamine Dimesylate Tablet, Chewableunavailable · for 3 days
• Lorazepam Injectionunavailable · for 3 days
• Meperidine Hydrochloride Injectionunavailable · for 3 days
• Methotrexate Sodium Injectionunavailable · for 3 days
• Methylphenidate Film, Extended Releaseunavailable · for 3 days
• Methylphenidate Hydrochloride Tablet, Extended Releaseunavailable · for 3 days
• Methylprednisolone Acetate Injectionunavailable · for 3 days
• Metronidazole Injectionunavailable · for 3 days
• Midazolam Hydrochloride Injectionunavailable · for 3 days
• Morphine Sulfate Injectionunavailable · for 3 days
• Penicillin G Benzathine Injectionunavailable · for 3 days
• Pentostatin Injectionunavailable · for 3 days
• Promethazine Hydrochloride Injectionunavailable · for 3 days
• Propranolol Hydrochloride Injectionunavailable · for 3 days
• Quinapril Hydrochloride Tabletunavailable · for 3 days
• Quinapril/Hydrochlorothiazide Tabletunavailable · for 3 days
• Remifentanil Hydrochloride Injectionunavailable · for 3 days
• Rifampin Capsuleunavailable · for 3 days
• Rifampin Injectionunavailable · for 4 days
• Riluzole Oral Suspensionunavailable · for 3 days
• Rocuronium Bromide Injectionunavailable · for 3 days
• Ropivacaine Hydrochloride Injectionunavailable · for 3 days
• Sodium Acetate Injectionunavailable · for 4 days
• Sodium Bicarbonate Injectionunavailable · for 4 days
• Sterile Water Injectionunavailable · for 3 days
• Sterile Water Irrigantunavailable · for 3 days
• Streptozocin Powder, For Solutionunavailable · for 3 days
• Sufentanil Citrate Injectionunavailable · for 3 days
• Technetium TC-99M Pyrophosphate Kit Injectionunavailable · for 3 days
• Triamcinolone Hexacetonide Injectionunavailable · for 3 days
• Valproate Sodium Injectionunavailable · for 3 days
• Acetaminophen; Oxycodone Hydrochloride Tabletlimited availability · for 4 days
• Activated Charcoal Oral Suspensionlimited availability · for 4 days
• Adalimumab-adaz Injectionlimited availability · for 4 days
• Adalimumab-ryvk Kitlimited availability · for 4 days
• Allopurinol Tabletlimited availability · for 4 days
• Alteplase Injectionlimited availability · for 3 days
• Ampicillin Sodium Injectionlimited availability · for 4 days
• Anagrelide Hydrochloride Capsulelimited availability · for 4 days
• Aprepitant Oral Powder for Suspensionlimited availability · for 3 days
• Arsenic Trioxide Injectionlimited availability · for 4 days
• Aspirin Suppositorylimited availability · for 3 days
• Atazanavir Sulfate; Cobicistat Tabletlimited availability · for 4 days
• Azithromycin Injectionlimited availability · for 3 days
• Azithromycin Tabletlimited availability · for 4 days
• Belladonna and Opium Suppositorylimited availability · for 4 days
• Bendamustine Hydrochloride Injection, Solutionlimited availability · for 3 days
• Benztropine Mesylate Injectionlimited availability · for 3 days
• Busulfan Injectionlimited availability · for 3 days
• Calcitriol Capsulelimited availability · for 4 days
• Calcium Chloride; Dextrose; Magnesium Chloride; Sodium Chloride; Sodium Lactate Intraperitoneal Injection, Solutionlimited availability · for 4 days
• Carbamazepine Capsule, Extended Releaselimited availability · for 4 days
• Caspofungin Acetate Injectionlimited availability · for 4 days
• Cefepime Hydrochloride Injectionlimited availability · for 4 days
• Ceftazidime Injectionlimited availability · for 4 days
• Cetrorelix Acetate Injectionlimited availability · for 4 days
• Chlorothiazide Oral Suspensionlimited availability · for 4 days
• Cisatracurium Besylate Injectionlimited availability · for 4 days
• Clindamycin Hydrochloride Capsulelimited availability · for 4 days
• Clindamycin Palmitate Hydrochloride Injectionlimited availability · for 3 days
• Crinecerfont Capsulelimited availability · for 3 days
• Dacomitinib Tabletlimited availability · for 4 days
• Dapsone Gellimited availability · for 3 days
• Daptomycin Injectionlimited availability · for 4 days
• Decitabine Injectionlimited availability · for 4 days
• Deferiprone Tabletlimited availability · for 3 days
• Dehydrated Alcohol Injection, Solutionlimited availability · for 4 days
• Desflurane Liquid for Inhalationlimited availability · for 4 days
• Dextrose Monohydrate, Sodium Chloride, Sodium Lactate, Calcium Chloride, Magnesium Chloride Solutionlimited availability · for 4 days
• Diclofenac Sodium Tablet, Delayed Releaselimited availability · for 4 days
• Diltiazem Hydrochloride Injectionlimited availability · for 4 days
• Disopyramide Phosphate Capsule, Extended Releaselimited availability · for 4 days
• Docetaxel Injectionlimited availability · for 4 days
• Donepezil Hydrochloride; Memantine Hydrochloride Capsule, Extended Releaselimited availability · for 4 days
• Doxercalciferol Injectionlimited availability · for 4 days
• Doxycycline Hyclate Tabletlimited availability · for 4 days
• Doxycycline Hyclate Tablet, Delayed Releaselimited availability · for 4 days
• Doxylamine Succinate and Pyridoxine Hydrochloride Tablet, Delayed Releaselimited availability · for 3 days
• Elbasvir; Grazoprevir Tabletlimited availability · for 4 days
• Emtricitabine Capsulelimited availability · for 4 days
• Emtricitabine Oral Solutionlimited availability · for 3 days
• Epinephrine Injectionlimited availability · for 4 days
• Etravirine Tabletlimited availability · for 4 days
• Everolimus Tabletlimited availability · for 4 days
• Felodipine Tablet, Extended Releaselimited availability · for 4 days
• Felodipine Tablet, Film Coated, Extended Releaselimited availability · for 4 days
• Fluocinonide Ointmentlimited availability · for 4 days
• Fluticasone Propionate and Salmeterol Xinafoate Aerosol, Meteredlimited availability · for 4 days
• Fluvastatin Sodium Tablet, Extended Releaselimited availability · for 4 days
• Fosaprepitant Dimeglumine Injectionlimited availability · for 3 days
• Frovatriptan Succinate Tabletlimited availability · for 4 days
• Fulvestrant Injectionlimited availability · for 3 days
• Gadobutrol Injectionlimited availability · for 4 days
• Gadoterate Meglumine Injectionlimited availability · for 4 days
• Gemfibrozil Tabletlimited availability · for 4 days
• Glyburide Tabletlimited availability · for 4 days
• Glycerol Phenylbutyrate Oral Liquidlimited availability · for 4 days
• Glycopyrrolate Injectionlimited availability · for 4 days
• Guanfacine Hydrochloride Tablet, Extended Releaselimited availability · for 4 days
• Haloperidol Decanoate Injectionlimited availability · for 4 days
• Hydrochlorothiazide Capsulelimited availability · for 4 days
• Hydrocortisone Acetate Suppositorylimited availability · for 4 days
• Hydromorphone Hydrochloride Suppositorylimited availability · for 4 days
• Hydroxychloroquine Sulfate Tabletlimited availability · for 4 days
• Icatibant Acetate Injectionlimited availability · for 4 days
• Icosapent Ethyl Capsulelimited availability · for 4 days
• Idelalisib Tabletlimited availability · for 4 days
• Imipenem and Cilastatin Injectionlimited availability · for 4 days
• Imipenem Anhydrous, Cilastatin, and Relebactam Anhydrous Injectionlimited availability · for 4 days
• Insulin Glargine Injectionlimited availability · for 4 days
• Insulin Glargine-aglr Injectionlimited availability · for 4 days
• Insulin Lispro Injectionlimited availability · for 4 days
• Insulin Lispro Protamine and Insulin Lispro Injectionlimited availability · for 3 days
• Insulin Lispro-aabc Injectionlimited availability · for 4 days
• Irinotecan Hydrochloride Injectionlimited availability · for 4 days
• Iron Sucrose Injectionlimited availability · for 3 days
• Itraconazole Capsulelimited availability · for 4 days
• Ivabradine Hydrochloride Tabletlimited availability · for 4 days
• Ivabradine Solutionlimited availability · for 4 days
• Ivermectin Tabletlimited availability · for 4 days
• Ketamine Hydrochloride Injectionlimited availability · for 3 days
• Ketorolac Tromethamine Tabletlimited availability · for 4 days
• Lamotrigine Tablet, Extended Releaselimited availability · for 4 days
• Lasmiditan Succinate Tabletlimited availability · for 4 days
• Leflunomide Tabletlimited availability · for 4 days
• Lincomycin Hydrochloride Injectionlimited availability · for 4 days
• Lopinavir and Ritonavir Oral Solutionlimited availability · for 4 days
• Lopinavir and Ritonavir Tabletlimited availability · for 4 days
• Lorlatinib Tabletlimited availability · for 4 days
• Maraviroc Solutionlimited availability · for 4 days
• Medroxyprogesterone Acetate Tabletlimited availability · for 4 days
• Melphalan Hydrochloride Injectionlimited availability · for 3 days
• Mesalamine Capsule, Extended Releaselimited availability · for 4 days
• Metoprolol Succinate Tablet, Extended Releaselimited availability · for 4 days
• Micafungin Sodium Injectionlimited availability · for 4 days
• Mirikizumab-mrkz Injectionlimited availability · for 4 days
• Montelukast Sodium Tablet, Chewablelimited availability · for 4 days
• Morphine Sulfate Suppositorylimited availability · for 4 days
• Morphine Sulfate Tabletlimited availability · for 4 days
• Moxifloxacin Injectionlimited availability · for 4 days
• Nebivolol Hydrochloride Tabletlimited availability · for 4 days
• Neostigmine Methylsulfate Injectionlimited availability · for 3 days
• Nilutamide Tabletlimited availability · for 4 days
• Nitrofurantoin Oral Suspensionlimited availability · for 4 days
• Nitroglycerin Ointmentlimited availability · for 3 days
• Oxaliplatin Injectionlimited availability · for 4 days
• Palbociclib Capsulelimited availability · for 3 days
• Palonosetron Hydrochloride Injectionlimited availability · for 3 days
• Palovarotene Capsulelimited availability · for 3 days
• Pemetrexed Disodium Injectionlimited availability · for 4 days
• Pentamidine Isethionate Injectionlimited availability · for 4 days
• Peritoneal Dialysis Solutionlimited availability · for 4 days
• Phenobarbital Tabletlimited availability · for 4 days
• Phenoxybenzamine Hydrochloride Capsulelimited availability · for 4 days
• Pilocarpine Hydrochloride Ophthalmic Solutionlimited availability · for 4 days
• Pindolol Tabletlimited availability · for 3 days
• Piperacillin and Tazobactam Injectionlimited availability · for 4 days
• Plerixafor Injectionlimited availability · for 4 days
• Podofilox Topical Gellimited availability · for 4 days
• Podophyllum Resin Topical Tincturelimited availability · for 3 days
• Polyethylene glycol 3350, Sodium Ascorbate, Sodium Sulfate Anhydrous, Ascorbic Acid, Sodium Chloride, and Potassium Chloride Oral Solutionlimited availability · for 3 days
• Posaconazole Injectionlimited availability · for 3 days
• Potassium Chloride Tablet, Extended Releaselimited availability · for 4 days
• Potassium Chloride, Sodium Chloride, Calcium Chloride, and Magnesium Chloride Injection, Solutionlimited availability · for 4 days
• Pramlintide Acetate Injectionlimited availability · for 4 days
• Prazosin Hydrochloride Capsulelimited availability · for 4 days
• Progesterone Vaginal Gellimited availability · for 4 days
• Ramelteon Tabletlimited availability · for 3 days
• Riboflavin 5-phosphate Ophthalmic Solutionlimited availability · for 3 days
• Ritonavir Oral Powderlimited availability · for 4 days
• Ritonavir Tabletlimited availability · for 4 days
• Rivaroxaban For Suspensionlimited availability · for 4 days
• Rivastigmine Film, Extended Releaselimited availability · for 3 days
• Scopolamine Transdermal Systemlimited availability · for 4 days
• Semaglutide Tabletlimited availability · for 4 days
• Sodium Oxybate Solutionlimited availability · for 4 days
• Somatropin Injectionlimited availability · for 4 days
• Spironolactone Tabletlimited availability · for 4 days
• Succinylcholine Chloride Injectionlimited availability · for 3 days
• Sulconazole Nitrate Solutionlimited availability · for 4 days
• Tazemetostat Hydrobromide Tabletlimited availability · for 3 days
• Tiagabine Hydrochloride Tabletlimited availability · for 4 days
• Tobramycin Sulfate Injectionlimited availability · for 3 days
• Tranylcypromine Sulfate Tabletlimited availability · for 4 days
• Travoprost Ophthalmic Solutionlimited availability · for 4 days
• Ursodiol Capsulelimited availability · for 3 days
• Valsartan Tabletlimited availability · for 4 days
• Vancomycin Hydrochloride Injectionlimited availability · for 4 days
• Verapamil Hydrochloride Injectionlimited availability · for 4 days
• Vigabatrin Oral Solutionlimited availability · for 4 days
• Voriconazole Injectionlimited availability · for 4 days

Data from the official shortage list. Not a treatment or substitution recommendation — please ask your pharmacist or doctor.